Buy Testoprop Online Without Prescription In New Zealand

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General Information

Testosterone was the first successfully synthesized anabolic steroid. Testosterone propionate is a fast-acting, short-ester, oil-based injectable testosterone compound that is commonly prescribed for the treatment of hypogonadism – low testosterone levels and various related symptoms in males. Buy Testoprop Online Without Prescription In New Zealand

Testosterone propionate was first described in 1935 to increase synthetic testosterone’s therapeutic usefulness by slowing its release into the bloodstream. It was released for clinical use two years later by Schering AG in Germany, featured in a hybrid blend with testosterone enanthate under the brand name Testoviron. Buy Testoprop Online Without Prescription In New Zealand This was also the first commercially available version on the U.S. prescription drug market and remained the dominant form of testosterone globally prior to 1960.

Cells in the adrenal cortex, ovary, and testis produce endogenous testosterone, the most common androgen in the human body. The treatment of either congenital or acquired hypogonadism involves the use of testosterone. The best exogenous androgen for postmenopausal women to use in the palliative management of breast cancer is testosterone. 1938 saw the introduction of testosterone, which the FDA approved in 1939. Anabolic steroids, which are testosterone derivatives, have been used illegally and are now considered restricted substances. In 1991, testosterone was designated as a restricted substance along with numerous anabolic steroids. Both standard and delayed-release (depot) dose versions of testosterone are supplied parenterally. In September 1995, the FDA initially approved testosterone transdermal patches (Androderm); many transdermal forms and brands are now available including implants, gels, and topical solutions. A testosterone buccal system, Striant, was FDA approved in July 2003; the system is a mucoadhesive product that adheres to the buccal mucosa and provides a controlled and sustained release of testosterone. In May 2014, the FDA approved an intranasal gel formulation (Natesto). A transdermal patch (Intrinsa) for hormone replacement in women is under investigation; the daily dosages used in women are much lower than for products used in males. The FDA ruled in late 2004 that it would delay the approval of Intrinsa women’s testosterone patch and has required more data regarding safety, especially in relation to cardiovascular and breast health. Buy Testoprop Online Without Prescription In New Zealand

Pharmacokinetics

Testosterone is administered intramuscularly (IM); via subcutaneous injection; to the skin as a topical gel, solution, ointment or transdermal systems for transdermal absorption; by implantation of long-acting pellets, or; via buccal systems. Buy Testoprop Online Without Prescription In New Zealand

In serum, testosterone is bound to protein. It has a high affinity for sex hormone binding globulin (SHBG) and a low affinity for albumin. The albumin-bound portion freely dissociates. The affinity for SHBG changes throughout life. It is high during prepuberty, declines during adolescence and adult life, then rises again in old age. The active metabolite DHT has a greater affinity for SHBG than testosterone. Elimination half-life is 10—100 minutes and is dependent on the amount of free testosterone in the plasma. Buy Testoprop Online Without Prescription In New Zealand

Testosterone is metabolized primarily in the liver to various 17-keto steroids. It is a substrate for hepatic cytochrome P450 (CYP) 3A4 isoenzyme.1 Estradiol and dihydrotestosterone (DHT) are the major active metabolites, and DHT undergoes further metabolism. Testosterone activity appears to depend on formation of DHT, which binds to cytosol receptor proteins. Further metabolism of DHT takes place in reproductive tissues. About 90% of an intramuscular testosterone dose is excreted in the urine as conjugates of glucuronic and sulfuric acids. About 6% is excreted in the feces, largely unconjugated. There is considerable variation in the half-life of testosterone as reported in the literature, ranging from 10 to 100 minutes.2

Affected cytochrome P450 isoenzymes and drug transporters: CYP3A4, P-gp

Testosterone is a substrate for CYP3A4 and is also both transported by and an inhibitor of P-glycoprotein (P-gp) transport.13

Route-Specific Pharmacokinetics

Intramuscular Route: Parenteral testosterone formulations have been developed that reduce the rate of testosterone secretion, with esters being less polar and slowly absorbed from intramuscular sites. Esters have a duration of action of 2—4 weeks following IM administration. The esters are hydrolyzed to free testosterone, which is inactivated in the liver. Buy Testoprop Online Without Prescription In New Zealand

Testoprop is injectable steroid which contains the hormone Testosterone Propionate in preparations of 100 mg per ML.

The Testoprop ester is much faster acting (2-3 days) than Enathate or Cypionate, and thus requires a more frequent injection schedule such as every day or every other day in order to keep blood levels as stable as possible. The benefit to this however, is that the steroid can be cleared from the body much more quickly after use is discontinued, thus making it a more preferable choice for tested athletes. Some bodybuilders also claim that Testosterone Propionate tends to induce far fewer estrogen related side effects such as bloat than do the other esters of this powerful hormone. Buy Testoprop Online Without Prescription In New Zealand

Testoprop is the most common anabolic hormone that there is and is also considered the most basic. Due to this, bodybuilders often consider it the base steroid to most all cycles. Testoprop is both anabolic and androgenic in nature. Users of this steroid will notice a dramatic gain in muscle size and strength, as well as an overall sense of well being and increases libido and sex drive.

Testoprop aromatizes very easily and therefore estrogen buildup and side effects can become an issue for users sensitive to these problems or those choosing to use a high dose of this compound. Therefore, when using Testosterone Propionate, bodybuilders often choose in incorporate an anti-estrogen such as Anastrozole, Proviron, Tamoxifen to help keep estrogen related side effects to a minimum. Extremely sensitive users, or users using very high doses (800-1200 mg) might find that stronger anti-estrogens such as Letrozole or Exemestane are more suitable. Androgenic side effects such as oily skin are also possible while taking Testosterone Propionate. Buy Testoprop Online Without Prescription In New Zealand

Testoprop use will quickly shut down the body’s natural production of the hormone, thus making a proper PCT plan essential for restoring the body’s natural function and maintaining gains as best as possible after use of the steroid has been discontinued. At cycle’s end, bodybuilders often choose to use a combination of Clomid, Tamoxifen, and HCG for a period of 3-4wks in order to restore pituitary gland and testes operation quickly and effectively.

Woman bodybuilders often use Testoprop to build mass, although of course the dosage is significantly less than what males would use due to the possibility of masculizing side effects.

The male bodybuilder’s dosage of Testoprop would typically be in 400-1200 mg per week range and cycle duration would be from 8-20 weeks, depending of course on the goals of the athlete. Women typically see desirable results from doses of 50-100 mg per